Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : HDAC8-IN-22d
Catalog No.: PC-63481Not For Human Use, Lab Use Only.
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3; shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); exhibits cytotoxicity against human lung CL1-5 cells (IC50=7.0 uM) similar to that of SAHA yet without significant cytotoxicity for normal IMR-90 cells.
| M.Wt | 345.398 | |
| Formula | C22H19NO3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Huang WJ, et al. ChemMedChem. 2012 Oct;7(10):1815-24.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
