Chemical Structure : HEAL-116
Catalog No.: PC-24810Not For Human Use, Lab Use Only.
HEAL-116 is a potent, selective 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor, shows binding specificity to the substrate-binding pocket of 3βHSD1 and effectively neutralizes the local charge environment.
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HEAL-116 is a potent, selective 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor, shows binding specificity to the substrate-binding pocket of 3βHSD1 and effectively neutralizes the local charge environment.
HEAL-116 robustly inhibits 3βHSD1 activity and exerts pronounced antitumor effect in biochemical, cellular, and mouse models.
M.Wt | 371.82 | |
Formula | C20H18ClNO4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. He D, et al. Proc Natl Acad Sci U S A. 2025 Jul;122(26):e2422267122.
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