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HG-7-27-01

Chemical Structure : HG-7-27-01

CAS No.: 1135270-45-9

HG-7-27-01 (c-Fes inhibitor)

Catalog No.: PC-61639Not For Human Use, Lab Use Only.

HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.

    Physicochemical Properties

    M.Wt 700.815
    Formula C37H43F3N10O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(1E)-2-[5-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-2-pyrazinyl]ethenyl]-

    References

    1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40.

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