HG-7-27-01 |CAS:1135270-45-9 Probechem Biochemicals

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Chemical Structure : HG-7-27-01

HG-7-27-01

Catalog No.: PC-61639Not For Human Use, Lab Use Only.

HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.

Physicochemical Properties

M.Wt	700.815
Formula	C37H43F3N10O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(1E)-2-[5-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-2-pyrazinyl]ethenyl]-

References

1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40.

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HG-7-27-01

Biological Activity

Physicochemical Properties

References

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