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HH-N25

Chemical Structure : HH-N25

CAS No.: 1643807-17-3

HH-N25 (HH N25)

Catalog No.: PC-72675Not For Human Use, Lab Use Only.

HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).

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    Biological Activity

    HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).
    HH-N25 shows potent antitumor activities in human breast cancer cells in vitro and in vivo.

    Physicochemical Properties

    M.Wt 402.896
    Formula C23H15ClN2OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(benzylamino)-10-chloro-12H-thiochromeno[2,3-c]quinolin-12-one

    References

    1. Bashir Lawal, et al. J Inflamm Res. 2021 Sep 22;14:4901-4913.

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