HH-N25 | TOP1 inhibitor | Probechem Biochemicals

Chemical Structure : HH-N25

HH-N25 (HH N25)

Catalog No.: PC-72675Not For Human Use, Lab Use Only.

HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).

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Biological Activity

HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).
HH-N25 shows potent antitumor activities in human breast cancer cells in vitro and in vivo.

Physicochemical Properties

M.Wt	402.896
Formula	C23H15ClN2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(benzylamino)-10-chloro-12H-thiochromeno[2,3-c]quinolin-12-one

References

1. Bashir Lawal, et al. J Inflamm Res. 2021 Sep 22;14:4901-4913.

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HH-N25 (HH N25)

Biological Activity

Physicochemical Properties

References

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