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HH044

Chemical Structure : HH044

CAS No.: 1544618-86-1

HH044

Catalog No.: PC-23979Not For Human Use, Lab Use Only.

HH044 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS) with Ki of 5 nM, >250-fold selective over iNOS and eNOS.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HH044 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS) with Ki of 5 nM, >250-fold selective over iNOS and eNOS.

Physicochemical Properties

M.Wt 459.63
Formula C25H25N5S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide

References

1. Tong S, et al. Sci Rep. 2022 Feb 1;12(1):1701.

2. Huang H, et al. J Med Chem. 2014 Feb 13;57(3):686-700.

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