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HIV-1 Integrase Inhibitor 1

Chemical Structure : HIV-1 Integrase Inhibitor 1

CAS No.: 2146094-22-4

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HIV-1 Integrase Inhibitor 1

Catalog No.: PC-60172Not For Human Use, Lab Use Only.

A novel compound that disrupts the HIV-1 integrase LEDGF interaction.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel compound that disrupts the HIV-1 integrase LEDGF interaction; produces an ALLINI-like phenotype through engagement of IN sites distinct from the LEDGF pocket.

Physicochemical Properties

M.Wt 480.579
Formula C26H28N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(4-(2'-(N-(tert-butyl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)propanoic acid

References

1. Burlein C, et al. ACS Chem Biol. 2017 Nov 17;12(11):2858-2865.

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