Chemical Structure : HIV capsid modulator 5-33d
Catalog No.: PC-27767Not For Human Use, Lab Use Only.
HIV capsid modulator 5-33d is a potent HIV capsid modulator, exhibits potent antiviral activity with EC50 of 0.14 uM, exhibits potent binding affinities to the CA hexamer with KD of 59.0 nM, but not CA monomer.
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HIV capsid modulator 5-33d is a potent HIV capsid modulator, exhibits potent antiviral activity with EC50 of 0.14 uM, exhibits potent binding affinities to the CA hexamer with KD of 59.0 nM, but not CA monomer.
5-33d exerts dual-stage inhibition by disrupting CA-host binding and modulating capsid assembly.
| M.Wt | 684.75 | |
| Formula | C32H31F3N6O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jiang X, et al. J Med Chem. 2026 Aug 13;69(15):18783-18799.

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