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Chemical Structure : HJC0416
Catalog No.: PC-60500Not For Human Use, Lab Use Only.
HJC0416 is an orally bioavailable small-molecule STAT3 inhibitor.
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HJC0416 is an orally bioavailable small-molecule STAT3 inhibitor.
HJC0416 inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively.
HJC0416 inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo.
| M.Wt | 392.854 | |
| Formula | C18H17ClN2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chen H, et al. Eur J Med Chem. 2014 Jul 23;82:195-203.
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