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Chemical Structure : HMCEF
Catalog No.: PC-60181Not For Human Use, Lab Use Only.
HMCEF is a small molecule P-selectin inhibitor that directly binds to P-selectin, intercalates into calf thymus DNA, cuts off DNA pBR22 and inhibits the proliferation of cancer cells.
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HMCEF is a small molecule P-selectin inhibitor that directly binds to P-selectin, intercalates into calf thymus DNA, cuts off DNA pBR22 and inhibits the proliferation of cancer cells.
HMCEF dose dependently inhibits inflammatory response of mice and inhibits thrombosis and inflammation, decreases serum TNFα and IL-8.
| M.Wt | 389.455 | |
| Formula | C23H23N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wu J, et al. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4631-6.
2. Wu J, et al. Drug Des Devel Ther. 2017 Jan 17;11:225-239.
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