HPP-9 | BET PROTAC | Probechem Biochemicals

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Chemical Structure : HPP-9

Catalog No.: PC-49328Not For Human Use, Lab Use Only.

HPP-9 is a potent BET bromodomain degrader that acts through a PROTAC mechanism, HPP-9 is a long-acting Hedgehog pathway inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HPP-9 is a potent BET bromodomain degrader that acts through a PROTAC mechanism, HPP-9 is a long-acting Hedgehog pathway inhibitor.

M.Wt	900.986
Formula	C49H52N6O11
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methoxyethyl 4-(3-((1-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

1. Meropi Bagka, et al. Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1.