HQA2 | UT-A inhibitor | Probechem Biochemicals

Chemical Structure : HQA2

HQA2 (UTAinh-A2, UTA1inh-A2 )

Catalog No.: PC-26602Not For Human Use, Lab Use Only.

UTAinh-A2 (HQA2) is a noncompetitive inhibitor of UT-A with IC50 of 5 uM for UT-A1, with10-fold selectivity against UT-B, inhibits urea transport mediated by hUT-A2 with IC50 of 3.66 uM.

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Biological Activity

UTAinh-A2 (HQA2) is a noncompetitive inhibitor of UT-A with IC50 of 5 uM for UT-A1, with10-fold selectivity against UT-B, inhibits urea transport mediated by hUT-A2 with IC50 of 3.66 uM.

Physicochemical Properties

M.Wt	308.34
Formula	C18H16N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	8-hydroxy-N-(3-methoxybenzyl)quinoline-2-carboxamide

References

1. Shen-Ming Huang, et al. Nat Commun. 2024 Nov 26;15(1):10226.

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HQA2 (UTAinh-A2, UTA1inh-A2 )

Biological Activity

Physicochemical Properties

References

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