Catalog No.: PC-38502Not For Human Use, Lab Use Only.
HS-1793 is a resveratrol derivative that overcomes the resistance conferred by Bcl-2 in U937 cells via 14-3-3, exhibits antitumor activity via Bad and marked downregulates 14-3-3 protein.
HS-1793 is a resveratrol derivative that overcomes the resistance conferred by Bcl-2 in U937 cells via 14-3-3, exhibits antitumor activity via Bad and marked downregulates 14-3-3 protein.
HS-1793 induced polyploid LNCaP prostate cancer cells are vulnerable to downregulation of Bcl-xL.
HS1793 disrupts the interaction between AKT and heat shock protein 90 and induces apoptotic cell death and cell cycle arrest through downregulation of AKT in human colon cancer cells.
HS1793 inhibits hypoxia-induced HIF-1α and VEGF expression, and migration in human prostate cancer cells.
Physicochemical Properties
M.Wt
252.269
Formula
C16H12O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(6-Hydroxy-2-naphthalenyl)1,3-benzenediol
References
1. Kim DH, et al. Int J Oncol. 2013 Dec;43(6):1915-24.
2. Jeong SH, et al. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4225-9.
3. Jeong SH, et al. Mol Cells. 2012 Oct;34(4):357-65.
4. Jeong SH, et al. Biochem Pharmacol. 2009 Apr 15;77(8):1337-47.
