Chemical Structure : HS-276
CAS No.: 2767422-72-8
Catalog No.: PC-73239Not For Human Use, Lab Use Only.
HS-276 is a potent, highly selective and orally bioavailable TAK1 inhibitor with Ki of 2.5 nM.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $188 | In stock | |
25 mg | $348 | In stock | |
50 mg | $558 | In stock | |
100 mg | $958 | In stock | |
200 mg | Get quote | ||
1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
HS-276 is a potent, highly selective and orally bioavailable TAK1 inhibitor with Ki of 2.5 nM.
HS-276 showed significant inhibition of TNF-mediated cytokine profiles in vitro (IC50=138 nM) and in vivo.
HS-276 demonstrated significant attenuation of arthritic-like symptoms in the CIA mouse model of inflammatory RA.
M.Wt | 419.529 | |
Formula | C24H29N5O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-(6-(piperidin-1-ylmethyl)-1-propyl-1H-benzo[d]imidazol-2-yl)isophthalamide |
1. Scott Scarneo, et al. ACS Chem Biol. 2022 Mar 18;17(3):536-544.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright