Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : HS-276
CAS No.: 2767422-72-8
Catalog No.: PC-73239Not For Human Use, Lab Use Only.
HS-276 is a potent, highly selective and orally bioavailable TAK1 inhibitor with Ki of 2.5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $428 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
HS-276 is a potent, highly selective and orally bioavailable TAK1 inhibitor with Ki of 2.5 nM.
HS-276 showed significant inhibition of TNF-mediated cytokine profiles in vitro (IC50=138 nM) and in vivo.
HS-276 demonstrated significant attenuation of arthritic-like symptoms in the CIA mouse model of inflammatory RA.
| M.Wt | 419.529 | |
| Formula | C24H29N5O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(6-(piperidin-1-ylmethyl)-1-propyl-1H-benzo[d]imidazol-2-yl)isophthalamide |
|
1. Scott Scarneo, et al. ACS Chem Biol. 2022 Mar 18;17(3):536-544.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
