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Chemical Structure : HSGN-94
Catalog No.: PC-38637Not For Human Use, Lab Use Only.
HSGN-94 is a potent lipoteichoic acid (LTA) biosynthesis inhibitor via direct binding to PgcA and downregulation of PgsA, exhibits potent antibacterial activity against both MRSA and VRE with MICs of 0.25 ug/mL.
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HSGN-94 is a potent lipoteichoic acid (LTA) biosynthesis inhibitor via direct binding to PgcA and downregulation of PgsA, exhibits potent antibacterial activity against both MRSA and VRE with MICs of 0.25 ug/mL.
HSGN-94 demonstrated potent biofilm inhibition activity against MRSA and VRE biofilms.
HSGN-94 potent synergized with the WTA inhibitor Tunicamycin in inhibiting MRSA and VRE biofilm formation.
| M.Wt | 508.516 | |
| Formula | C23H23F3N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. George A Naclerio, et al. Molecules. 2020 May 12;25(10):2277.
2. Naclerio GA, et al. J Med Chem. 2022 Apr 28. doi: 10.1021/acs.jmedchem.1c02034.
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