Chemical Structure : HSK0935
Catalog No.: PC-61130Not For Human Use, Lab Use Only.
HSK0935 is a potent and highly selective SGLT2 inhibitor with IC50 of 1.3 nM, >800-fold selectivity over SGLT1 (IC50>1 uM).
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HSK0935 is a potent and highly selective SGLT2 inhibitor with IC50 of 1.3 nM, >800-fold selectivity over SGLT1 (IC50>1 uM).
HSK0935 shows robust urinary glucose excretion in Sprague-Dawley (SD) rats and affects more urinary glucose excretion in Rhesus monkeys.
M.Wt | 436.885 | |
Formula | C22H25ClO7 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Li Y, et al. J Med Chem. 2017 May 25;60(10):4173-4184.
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