Chemical Structure : HWL-088
CAS No.:
2378617-96-8
HWL-088
(HWL088)
Catalog No. : PC-24882Not For Human Use, Lab Use Only.
HWL-088 is a potent, selective and orally active FFAR1 (FFA1, GPR40) agonist with EC50 of 19 nM, has moderate PPARδ activity (EC50=570.9 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2488201
Biological Activity
HWL-088 is a potent, selective and orally active FFAR1 (FFA1, GPR40) agonist with EC50 of 19 nM, has moderate PPARδ activity (EC50=570.9 nM).
Physicochemical Properties
M.Wt
366.39
Formula
C22H19FO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(2-fluoro-4-((2'-methyl-[1,1'- biphenyl]-3-yl)methoxy)phenoxy)acetic acid
References
1. Li Z, et al. Bioorg Chem. 2019 Nov;92:103209.
2. Chen Y, et al. Br J Pharmacol. 2020 May;177(10):2286-2302.
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