Hedgehog-IN-7d |CAS:330796-24-2 Probechem Biochemicals

Chemical Structure : Hedgehog-IN-7d

Hedgehog-IN-7d (Gli inhibitor 7d)

Catalog No.: PC-62175Not For Human Use, Lab Use Only.

Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM..

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Biological Activity

Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM.

Physicochemical Properties

M.Wt	490.8
Formula	C23H15ClF4N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-urea

References

1. Brunton SA, et al. J Med Chem. 2008 Mar 13;51(5):1108-10.

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Hedgehog-IN-7d (Gli inhibitor 7d)

Biological Activity

Physicochemical Properties

References

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