Chemical Structure : Hemin
CAS No.: 16009-13-5
Catalog No.: PC-45633Not For Human Use, Lab Use Only.
Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
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Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
Hemin increases the size of autophagic vacuoles and induces mitophagy in K562 cells; a heme oxygenase (HO)‑1 inducer.
M.Wt | 651.9403 | |
Formula | C34H32ClFeN4O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 6.6 mg/mL |
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Chemical Name/SMILES |
Ferrate(2-), chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-5-13)- |
1. Fader CM, et al. Biol Cell. 2016 Apr;108(4):77-95.
2. Higdon AN, et al. Am J Physiol Heart Circ Physiol. 2012 Apr 1;302(7):H1394-409.
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