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Heterotaxin

Chemical Structure : Heterotaxin

CAS No.: 886862-25-5

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Heterotaxin

Catalog No.: PC-62436Not For Human Use, Lab Use Only.

Heterotaxin is a pyridine analog that inhibits TGF-β signaling, perturbs vascular development, melanogenesis, cell migration, and adhesion, and indirectly inhibit the phosphorylation of an intracellular mediator of TGF-β signaling.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Heterotaxin is a pyridine analog that inhibits TGF-β signaling, perturbs vascular development, melanogenesis, cell migration, and adhesion, and indirectly inhibit the phosphorylation of an intracellular mediator of TGF-β signaling.
    Heterotaxin possesses highly desirable antitumor properties, inhibits epithelial-mesenchymal transition, angiogenesis, and tumor cell proliferation in mammalian systems.

    Physicochemical Properties

    M.Wt 193.29
    Formula C12H19NO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-Butyl-6-ethyl-2-pyridinemethanol

    References

    1. Dush MK, et al. Chem Biol. 2011 Feb 25;18(2):252-63.

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