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Chemical Structure : Hydrastine
CAS No.: 118-08-1
Catalog No.: PC-46979Not For Human Use, Lab Use Only.
An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Hydrastine is an alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system.
Hydrastine inhibits PAK4 kinase activity, suppresses the proliferation and invasion of human lung adenocarcinoma cells, inhibits expression of cyclin D1/D3 and CDK2/4/6, leading to cell cycle arrest at the G1 phase.
Hydrastine also promotes the early apoptosis of lung adenocarcinoma cells through the mitochondrial apoptosis pathway.
| M.Wt | 383.3945 | |
| Formula | C21H21NO6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)- |
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1. Guo B, et al. Oncol Rep. 2016 Apr;35(4):2246-56.
2. Song S, et al. Org Biomol Chem. 2015 Mar 28;13(12):3803-18.
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