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Hydroxychloroquine

Chemical Structure : Hydroxychloroquine

CAS No.: 118-42-3

Hydroxychloroquine

Catalog No.: PC-27850Not For Human Use, Lab Use Only.

Hydroxychloroquine is a synthetic antimalarial drug that inhibits autophagy, also inhibits TLR7 and TLR9 signaling, also inhibits peptidyl arginine deiminase 4 (PAD4).

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Biological Activity

Hydroxychloroquine is a synthetic antimalarial drug that inhibits autophagy, also inhibits TLR7 and TLR9 signaling, also inhibits peptidyl arginine deiminase 4 (PAD4).

Physicochemical Properties

M.Wt 335.88
Formula C18H26ClN3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol

References

1. Lamphier M, et al. Mol Pharmacol. 2014 Mar;85(3):429-40.

2. Piconi S, et al. Blood. 2011 Sep 22;118(12):3263-72.

3. Noman MZ, et al. Cancer Res. 2011 Sep 15;71(18):5976-86.

4. Boya P, et al. Mol Cell Biol. 2005 Feb;25(3):1025-40.

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