Chemical Structure : Hygromycin B
CAS No.: 31282-04-9
Catalog No.: PC-24308Not For Human Use, Lab Use Only.
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells, also an inhibitor of the STAT3-CCD domain, disrupts the CHI3L1-STAT3 interaction, inhibits glioblastoma both in vitro and in vivo.
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|---|---|---|---|
| 250 mg | $48 | In stock | |
| 1 g | $88 | In stock | |
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Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells, also an inhibitor of the STAT3-CCD domain, disrupts the CHI3L1-STAT3 interaction, inhibits glioblastoma both in vitro and in vivo.
| M.Wt | 527.52 | |
| Formula | C20H37N3O13 | |
| Appearance | Solid | |
| Storage | 
                            
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| Solubility | 
                             10 mM in DMSO  | 
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| Chemical Name/SMILES | 
                             (3aS,3'R,4S,4'S,5'R,6R,6'R,7S,7aS)-4-(((1R,2S,3R,5S,6R)-3-Amino-2,6-dihydroxy-5-(methylamino)cyclohexyl)oxy)-6'-((S)-1-amino-2-hydroxyethyl)-6-(hydroxymethyl)octahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetraol  | 
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1. Yu W, et al. Dev Cell. 2025 Feb 7:S1534-5807(25)00034-6.

                
                
                
                
                
                
                
                
            
            
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