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I-229

Chemical Structure : I-229

CAS No.: 1801903-15-0

I-229 (I 229)

Catalog No.: PC-20374Not For Human Use, Lab Use Only.

I-229 is a potent and selective inhibitor of Vps34.

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5 mg $358 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

I-229 is a potent and selective inhibitor of Vps34.

Physicochemical Properties

M.Wt 502.92
Formula C22H17ClF2N6O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(6-chloro-4-methyl-2'-((2-methylpyrimidin-4-yl)amino)-[3,4'-bipyridin]-5-yl)-2,4-difluorobenzenesulfonamide

References

1. Dennis X Hu, et al. J Med Chem. 2022 Sep 8;65(17):11500-11512.

2. Patent WO2018144791 A1.

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