IACS-8803 disodium | STING agonist | Probechem Biochemicals

Chemical Structure : IACS-8803 disodium

Catalog No.: PC-22635Not For Human Use, Lab Use Only.

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist, shows robust activation of the STING pathway.

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Biological Activity

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist, shows robust activation of the STING pathway.

M.Wt	738.52
Formula	C20H23FN10O9P2S2.2Na
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	OC1[C@@]2([C@@H](O[C@@]1(COP(=O)(S)O[C@@]3([C@@](COP(=O)(S)O2)(O[C@H]([C@@H]3F)N4C=5C(N=C4)=C(N)N=CN5)[H])[H])[H])N6C=7C(N=C6)=C(N)N=CN7)[H].[Na]

1. Ager CR, et al. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

2. Ager CR, et al. J Immunother Cancer. 2021 Aug;9(8):e003246.