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Chemical Structure : IBMX
CAS No.: 28822-58-4
Catalog No.: PC-42971Not For Human Use, Lab Use Only.
IBMX (Isobutylmethylxanthine, Methylisobutylxanthine, NSC165960) is a broad-spectrum inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) with IC50 of 5-50 uM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $85 | In stock | |
| 250 mg | $135 | In stock | |
| 500 mg | $185 | In stock | |
| 1 g | Get quote |
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IBMX (Isobutylmethylxanthine, Methylisobutylxanthine, NSC165960) is a broad-spectrum inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) with IC50 of 5-50 uM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11.
IBMX is insensitive to PDE8A, PDE8B, and PDE9; increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases.
| M.Wt | 222.2438 | |
| Formula | C10H14N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 35 mg/mL |
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| Chemical Name/SMILES |
1H-Purine-2,6-dione, 3,9-dihydro-1-methyl-3-(2-methylpropyl)- |
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1. Snyder SH, et al. Proc Natl Acad Sci U S A. 1981 May;78(5):3260-4.
2. Kawabata A, et al. Thromb Res. 2001 Mar 15;101(6):513-5.
3. Tio M, et al. PLoS One. 2010 Feb 24;5(2):e9398.
4. Wu BN, et al. Br J Pharmacol. 2004 Aug;142(7):1105-14.
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