Chemical Structure : ICOS inhibitor 9
Catalog No.: PC-22944Not For Human Use, Lab Use Only.
ICOS inhibitor 9 is a small molecule inhibitor of ICOS/ICOS-L interaction with IC50 of 29.38 uM.
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ICOS inhibitor 9 is a small molecule inhibitor of ICOS/ICOS-L interaction with IC50 of 29.38 uM.
Inducible T cell co-stimulator (ICOS) is a positive immune checkpoint receptor expressed on the surface of activated T cells, which could promote cell function after being stimulated with ICOS ligand (ICOS-L).
M.Wt | 349.21 | |
Formula | C17H14Cl2N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Zhang L, et al. bioRxiv [Preprint]. 2024 Aug 7:2024.08.04.606538.
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