Chemical Structure : IDE1
CAS No.: 1160927-48-9
Catalog No.: PC-42193Not For Human Use, Lab Use Only.
IDE1 (Inducer of definitive endoderm 1) small molecule that can induce definitive endoderm from embryonic stem cells, induces the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse ESCs in vitro with EC50 of 125.5 nM.
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IDE1 (Inducer of definitive endoderm 1) small molecule that can induce definitive endoderm from embryonic stem cells, induces the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse ESCs in vitro with EC50 of 125.5 nM.
IDE1 induces phosphorylation of Smad2 and activate TGF-β signaling.
M.Wt | 306.3138 | |
Formula | C15H18N2O5 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 30 mg/mL |
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Chemical Name/SMILES |
Heptanedioic acid, 1-[2-[(2-carboxyphenyl)methylene]hydrazide] |
1. Borowiak M, et al. Cell Stem Cell. 2009 Apr 3;4(4):348-58.
2. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.
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