IDO-IN-1 | IDO inhibitor | Probechem Biochemicals

Chemical Structure : IDO-IN-1

CAS No.: 914638-30-5

IDO-IN-1 (IDO inhibitor 1)

Catalog No.: PC-46003Not For Human Use, Lab Use Only.

IDO-IN-1 is a potent, competitive indoleamine 2,3-dioxygenase (IDO) inhibitor with Hela IC50 of 19 nM.

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$218	In stock
25 mg	$358	In stock
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Biological Activity

IDO-IN-1 is a potent, competitive indoleamine 2,3-dioxygenase (IDO) inhibitor with Hela IC50 of 19 nM.
IDO-IN-1 decreases kynurenine levels by >50% in plasma and inhibits B16-GM-CSF tumor growth in a dose dependent fashion.

Physicochemical Properties

M.Wt	316.0866
Formula	C9H7BrFN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 682 mg/mL
Chemical Name/SMILES	1,2,5-Oxadiazole-3-carboximidamide, 4-amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-

References

1. Yue EW, et al. J Med Chem. 2009 Dec 10;52(23):7364-7.

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IDO-IN-1 (IDO inhibitor 1)

Biological Activity

Physicochemical Properties

References

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