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Chemical Structure : IDO2 inhibitor 22
Catalog No.: PC-23332Not For Human Use, Lab Use Only.
IDO2 inhibitor 22 is a selective iIndoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with IC50 of 112 nM and 411 nM for IDO2 and IDO1 respectively.
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IDO2 inhibitor 22 is a selective indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with IC50 of 112 nM and 411 nM for IDO2 and IDO1 respectively.
IDO2 inhibitor 22 alleviated disease severity and reduced inflammatory cytokines in both the collagen-induced arthritis (CIA) mice model and adjuvant arthritis (AA) rat model.
| M.Wt | 541.37 | |
| Formula | C21H21BrN10O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. He G, et al. J Med Chem. 2022 Nov 10;65(21):14348-14365.
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