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IDRA-21

Chemical Structure : IDRA-21

CAS No.: 22503-72-6

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IDRA-21 (IDRA21)

Catalog No.: PC-61721Not For Human Use, Lab Use Only.

IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR).
IDRA-21 demonstrates nootropic effects in animal studies, significantly improving learning and memory.
IDRA-21 is 10-30 times more potent than Aniracetam in reversing cognitive deficits induced by alprazolam or scopolamine.

Physicochemical Properties

M.Wt 232.687
Formula C8H9ClN2O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide

References

1. Zivkovic I, et al. J Pharmacol Exp Ther. 1995 Jan;272(1):300-9.

2. Thompson DM, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7667-71.

3. Impagnatiello F, et al. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):7053-8.

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