Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-HIV-IDX899
IDX899

Chemical Structure : IDX899

CAS No.: 1018450-26-4

Add to Favorites

IDX899 (IDX-899;IDX 899;Fosdevirine;GSK 2248761)

Catalog No.: PC-60468Not For Human Use, Lab Use Only.

IDX899 (Fosdevirine, GSK 2248761) is a novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively.

Packing Price Stock Quantity
5 mg Get quote
10 mg Get quote
25 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    IDX899 (Fosdevirine, GSK 2248761) is a novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively.
    IDX899 (Fosdevirine, GSK 2248761) shows substantial benefits in term of HIV mutant activities, physicochemical properties and pharmacological profile.

    Physicochemical Properties

    M.Wt 413.798
    Formula C20H17ClN3O3P
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-chloro-3-[[3-[(E)-2-cyanovinyl]-5-methyl-phenyl]-(R)-methoxy-phosphoryl]-1H-indole-2-carboxamide

    References

    1. Dousson C, et al. J Med Chem. 2016 Mar 10;59(5):1891-8.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: