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IFNAR-IN-1

Chemical Structure : IFNAR-IN-1

CAS No.: 844882-93-5

IFNAR-IN-1 (IFN-alpha and IFNAR interaction inhibitor)

Catalog No.: PC-43246Not For Human Use, Lab Use Only.

IFNAR-IN-1 is a nonpeptidic, small molecule inhibitor of IFN-α and IFNAR interaction, specifically inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IFNAR-IN-1 is a nonpeptidic, small molecule inhibitor of IFNα and IFNAR interaction, specifically inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 uM.

Physicochemical Properties

M.Wt 279.3993
Formula C18H17NS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzenemethanamine, N-methyl-2-(1-naphthalenylthio)-

References

1. Geppert T, et al. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):258-61.

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