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IITR06144

Chemical Structure : IITR06144

CAS No.: 89076-51-7

IITR06144

Catalog No.: PC-38648Not For Human Use, Lab Use Only.

IITR06144 is a novel nitrofuran and exhibits broad-spectrum bactericidal activity against most MDR bacteria (MIC, 0.5 mg/mL).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

IITR06144 is a novel nitrofuran and exhibits broad-spectrum bactericidal activity against most MDR bacteria (MIC, 0.5 mg/mL).
IITR06144 retained its potency against nitrofurantoin-resistant clinical isolates.
IITR06144 displayed anti-persister, anti-biofilm activity and lack of spontaneous resistance development.
IITR06144 demonstrated a large therapeutic index with no associated in vitro and in vivo toxicity.

Physicochemical Properties

M.Wt 260.205
Formula C12H8N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-2-nitro-5-(4-nitrostyryl)furan

References

1. Timsy Bhando, et al. J Antimicrob Chemother. 2020 Feb 1;75(2):418-428.

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