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IL-17A PPIm 23

Chemical Structure : IL-17A PPIm 23

CAS No.: 2446803-65-0

IL-17A PPIm 23 (LP0200 active drug)

Catalog No.: PC-47087Not For Human Use, Lab Use Only.

IL-17A PPIm 23 is a potent, orally bioavailable, small-molecule protein-protein interaction modulator (PPIm) of IL-17A, shows potential treatment of psoriasis and other inflammatory diseases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IL-17A PPIm 23 (LP0200 active drug) is a potent, orally bioavailable, small-molecule protein-protein interaction modulator (PPIm) of IL-17A, shows potential treatment of psoriasis and other inflammatory diseases.

Physicochemical Properties

M.Wt 474.609
Formula C27H34N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(1,1-dicyclopropyl-3-((4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl)amino)-3-oxopropan-2-yl)-1-isopropyl-1H-pyrazole-5-carboxamide

References

1. Andrews MD, et al. J Med Chem. 2022 Jun 29. doi: 10.1021/acs.jmedchem.2c00422.

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