Catalog No.: PC-35158Not For Human Use, Lab Use Only.
IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex, inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM).
IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex, inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM).
IMB-301 restores hA3G expression in the presence of Vif through disruption of the Vif-hA3G interaction.
IMB-301 significantly increases the amount of hA3G-HA in the virions; directly binds to hA3G with of 15.6 uM.
