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Chemical Structure : IMP-1700
Catalog No.: PC-20571Not For Human Use, Lab Use Only.
IMP-1700 (IMP1700) is a potent, cell-active inhibitor of bacterial AddAB-mediated DNA repair, sensitizes MRSA to ciprofloxacin (CFX) with an EC50 of 5.9 nM.
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IMP-1700 (IMP1700) is a potent, cell-active inhibitor of bacterial AddAB-mediated DNA repair, sensitizes MRSA to ciprofloxacin (CFX) with an EC50 of 5.9 nM.
IMP-1700 is a high potency potentiator of DNA damage in bacterial cells.
IMP-1700 inhibits the bacterial SOS-response to DNA damage.
IMP-1700 demonstrates potential as a combinational therapy to combat serious drug-resistant infections.
IMP-1700 is a small molecule inhibitor of the AddAB/RecBCD DNA repair complexes.
| M.Wt | 534.53 | |
| Formula | C25H22F4N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Carine S Q Lim, et al. Bioorg Med Chem. 2019 Oct 15;27(20):114962.
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