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IMP7068

Chemical Structure : IMP7068

CAS No.: 2226938-19-6

IMP7068 (Potrasertib, IMP-7068)

Catalog No.: PC-28172Not For Human Use, Lab Use Only.

Potrasertib (MP7068) is a potent and selective WEE1 inhibitor, exhibits superior WEE1/PLK1 selectivity (>435 fold), shows potent cytotoxicity against a wide range of cancer cell lines.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Potrasertib (MP7068) is a potent and selective WEE1 inhibitor, exhibits superior WEE1/PLK1 selectivity (>435 fold), shows potent cytotoxicity against a wide range of cancer cell lines.

Physicochemical Properties

M.Wt 565.50
Formula C28H30Cl2N8O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(2,6-dichlorophenyl)-2-((3-methyl-4-((3S,5R)-3,4,5-trimethylpiperazin-1-yl)phenyl)amino)-8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one

References

1. Sui Xiong Cai, et al. Cancer Res (2023) 83 (7_Supplement): 3091.

2. Patent WO2022188802 A1 2022-09-15.

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