IMPDH2-IN-5 |CAS:2119603-25-5 Probechem Biochemicals

Chemical Structure : IMPDH2-IN-5

IMPDH2-IN-5 (IMPDH2 inhibitor)

Catalog No.: PC-70215Not For Human Use, Lab Use Only.

IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).

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Biological Activity

IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).
IMPDH2-IN-5 is a Sappanone A derivative.

Physicochemical Properties

M.Wt	302.257
Formula	C16H11FO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(3,4-dihydroxybenzylidene)-5-fluoro-7-hydroxychroman-4-one

References

1. Liao LX, et al. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5986-E5994.

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IMPDH2-IN-5 (IMPDH2 inhibitor)

Biological Activity

Physicochemical Properties

References

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