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IN-1233

Chemical Structure : IN-1233

CAS No.: 1093952-95-4

IN-1233 (IN1233;IN 1233)

Catalog No.: PC-61447Not For Human Use, Lab Use Only.

IN-1233 is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    IN-1233 is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

    Physicochemical Properties

    M.Wt 419.488
    Formula C26H21N5O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide

    References

    1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.12120361

    2. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.

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