IN-1233 phosphate | ALK5 inhibitor | Probechem Biochemicals

Chemical Structure : IN-1233 phosphate

IN-1233 phosphate (IN1233, IN 1233)

Catalog No.: PC-61448Not For Human Use, Lab Use Only.

IN-1233 phosphate is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

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Biological Activity

IN-1233 phosphate is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

Physicochemical Properties

M.Wt	517.482
Formula	C26H24N5O5P
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide phosphate

References

1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.12120361

2. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.

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IN-1233 phosphate (IN1233, IN 1233)

Biological Activity

Physicochemical Properties

References

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