Chemical Structure : INCB13739
CAS No.: 872506-67-7
Catalog No.: PC-35575Not For Human Use, Lab Use Only.
INCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors..
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INCB13739 (INCB-13739) is a potent, selective, oral 11β-HSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.
M.Wt | 398.946 | |
Formula | C19H27ClN2O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3S)-1-[(3-Chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-3-piperidinecarboxamide |
1. Rosenstock J, et al. Diabetes Care. 2010 Jul;33(7):1516-22.
2. Ge R, et al. Curr Med Chem. 2010;17(5):412-22.
3. Anagnostis P, et al. Metabolism. 2013 Jan;62(1):21-33.
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