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IND-114338

Chemical Structure : IND-114338

CAS No.: 1426259-35-9

IND-114338 (IND 114338;IND114338)

Catalog No.: PC-60646Not For Human Use, Lab Use Only.

IND-114338 is a novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    IND-114338 is a novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.

    Physicochemical Properties

    M.Wt 344.436
    Formula C20H16N4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(6-methylpyridin-2-yl)-4-(4-(pyridin-3-yl)phenyl)thiazol-2-amine

    References

    1. Giles K, et al. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12.

    2. Li Z, et al. ChemMedChem. 2013 May;8(5):847-57.

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