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Chemical Structure : IND125
Catalog No.: PC-60645Not For Human Use, Lab Use Only.
IND125 is a potent, brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum.
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IND125 is a potent, brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum.
IND125 prolongs the lives of mice expressing a chimeric human/mouse PrP transgene inoculated with Creutzfeldt-Jakob disease prions.
| M.Wt | 386.429 | |
| Formula | C21H14N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Giles K, et al. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12.
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