Chemical Structure : IND125
Catalog No.: PC-60645Not For Human Use, Lab Use Only.
IND125 is a potent, brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
IND125 is a potent, brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum.
IND125 prolongs the lives of mice expressing a chimeric human/mouse PrP transgene inoculated with Creutzfeldt-Jakob disease prions.
M.Wt | 386.429 | |
Formula | C21H14N4O2S | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Giles K, et al. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright