Chemical Structure : INY-05-040
Catalog No.: PC-24888Not For Human Use, Lab Use Only.
INY-05-040 is a second-generation pan-AKT PROTAC degrader, selectively and rapidly (<5 h) degrades all three AKT isoforms and inhibits downstream signaling and cell proliferation in 288 cancer cell lines.
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INY-05-040 is a second-generation pan-AKT PROTAC degrader, selectively and rapidly (<5 h) degrades all three AKT isoforms and inhibits downstream signaling and cell proliferation in 288 cancer cell lines.
M.Wt | 1026.78 | |
Formula | C55H76ClN9O6S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Emily C Erickson, et al. Sci Signal. 2024 Feb 27;17(825):eadf2670.
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