Chemical Structure : IRAP-IN-1
Catalog No.: PC-72273Not For Human Use, Lab Use Only.
IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.
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IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.
IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy.
M.Wt | 597.696 | |
Formula | C35H40N3O4P | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Paraskevi Kokkala, et al. J Med Chem. 2016 Oct 13;59(19):9107-9123.
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