IS-741 |CAS:141283-87-6 Probechem Biochemicals

Chemical Structure : IS-741

CAS No.: 141283-87-6

Catalog No.: PC-36093Not For Human Use, Lab Use Only.

IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2)..

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Biological Activity

IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).

M.Wt	379.398
Formula	C15H20F3N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-(ethanesulfonamido)-5-(trifluoromethyl)pyridin-3-yl]cyclohexanecarboxamide

1. Yotsuya S, et al. Digestion. 1999;60 Suppl 1:34-9.

2. Yamauchi J, et al. Digestion. 1999;60 Suppl 1:40-6.

3. Kimura H, et al. Chem Pharm Bull (Tokyo). 1995 Oct;43(10):1696-700.

4. Kaku T, et al. Pancreas. 2007 Apr;34(3):299-309.