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Chemical Structure : IT-603
Catalog No.: PC-70271Not For Human Use, Lab Use Only.
A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays.
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A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays; inhibits human diffuse large B-cell lymphoma (DLBCL) cell line with IC50 of 18 uM, binds c-Rel directly and changes the conformation of the protein, inhibiting DNA binding and transcriptional activity.
| M.Wt | 329.168 | |
| Formula | C11H9BrN2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shono Y, et al. Cancer Discov. 2014 May;4(5):578-91.
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