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Chemical Structure : IT-901
Catalog No.: PC-61961Not For Human Use, Lab Use Only.
IT-901 is a novel potent, small molecule inhibitor of NF-κB subunit c-Rel, inhibits DNA binding of c-Rel and NF-κB activity with IC50 of 3 uM.
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IT-901 is a novel potent, small molecule inhibitor of NF-κB subunit c-Rel, inhibits DNA binding of c-Rel and NF-κB activity with IC50 of 3 uM; reduces stimulation of the oxidative stress response gene heme oxygenase-1, inhibits c-Rel/NF-κB both in vitro and in vivo.
| M.Wt | 342.37 | |
| Formula | C17H14N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shono Y, et al. Cancer Res. 2016 Jan 15;76(2):377-89.
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