ITF3756 | HDAC6 inhibitor | Probechem Biochemicals

Chemical Structure : ITF3756

CAS No.: 2247608-27-9

ITF3756 (ITF-3756)

Catalog No.: PC-24773Not For Human Use, Lab Use Only.

ITF3756 (ITF-3756) is a potent, selective HDAC6 inhibitor with IC50 of 17 nM, >80-fold selective versus HDAC8 and HDAC Class IIa isoforms (HDAC4, 5, 7, and 9).

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
50 mg	$428	In stock
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Biological Activity

ITF3756 (ITF-3756) is a potent, selective HDAC6 inhibitor with IC50 of 17 nM, >80-fold selective versus HDAC8 and HDAC Class IIa isoforms (HDAC4, 5, 7, and 9).

Physicochemical Properties

M.Wt	301.32
Formula	C13H11N5O2S:
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]-

References

1. Sandrone G, et al. ACS Med Chem Lett. 2021 Oct 11;12(11):1810-1817.

2. Zamperla MG, et al. Clin Epigenetics. 2024 Aug 18;16(1):109.

3. Barbara Vergani, et al. J Med Chem. 2019 Dec 12;62(23):10711-10739.

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ITF3756 (ITF-3756)

Biological Activity

Physicochemical Properties

References

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