ITSA-1 | HDAC activator | Probechem Biochemicals

Chemical Structure : ITSA-1

CAS No.: 200626-61-5

ITSA-1 (ITSA1, ITSA 1)

Catalog No.: PC-42181Not For Human Use, Lab Use Only.

ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.

Packing	Price	Stock
25 mg	$58	In stock
50 mg	$88	In stock
100 mg	$138	In stock
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Biological Activity

ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.
ITSA-1 also suppresses acetylation of cytoplasmic alpha-tubulin as well as histones induced by hydroxamic acid-based HDAC inhibitors like TSA and SAHA.

Physicochemical Properties

M.Wt	292.1202
Formula	C13H7Cl2N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 32 mg/mL
Chemical Name/SMILES	Methanone, 1H-benzotriazol-1-yl(2,4-dichlorophenyl)-

References

1. Koeller KM, et al. Chem Biol. 2003 May;10(5):397-410.

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ITSA-1 (ITSA1, ITSA 1)

Biological Activity

Physicochemical Properties

References

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