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Chemical Structure : ITSA-1
CAS No.: 200626-61-5
Catalog No.: PC-42181Not For Human Use, Lab Use Only.
ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.
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ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.
ITSA-1 also suppresses acetylation of cytoplasmic alpha-tubulin as well as histones induced by hydroxamic acid-based HDAC inhibitors like TSA and SAHA.
| M.Wt | 292.1202 | |
| Formula | C13H7Cl2N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
Methanone, 1H-benzotriazol-1-yl(2,4-dichlorophenyl)- |
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1. Koeller KM, et al. Chem Biol. 2003 May;10(5):397-410.
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